October 23, 2024
Re-engineered, blue light-activated immune cells penetrate and kill solid tumors
A team led by researchers from the Penn State College of Medicine re-engineered immune cells with a light-activated switch that modulates protein function and cellular behavior. When exposed to blue light, the cells change shape, infiltrating solid tumors grown in the lab and killing them.
![<p>A team led by researchers from the Penn State College of Medicine re-engineered immune cells with a light-activated switch that modulates protein function and cellular behavior. When exposed to blue light, the cells change shape, infiltrating solid tumors grown in the lab and killing them.</p>](https://gradschool.psu.edu/assets/uploads/news/_860xAUTO_fit_center-center_80_none/gettyimages-sean-anthony-eddy-h586f5f76itokVxUb81Bp.png)
A team led by researchers from the Penn State College of Medicine re-engineered immune cells with a light-activated switch that modulates protein function and cellular behavior. When exposed to blue light, the cells change shape, infiltrating solid tumors grown in the lab and killing them.
Credit: https://www.psu.edu/news/research/story/re-engineered-blue-light-activated-immune-cells-penetrate-and-kill-solid-tumors